Figure It is considered best to take nattokinase after dinner or before bed, as a thrombus is more likely to occur around midnight or early in the morning. From afternoon to night, serotonin is transformed into melatonin. Melatonin is known for its sleep-stimulating effects. If you want to sleep well at the end of the day, we recommend eating natto at bedtime lunch.
The enzymatic activity of oral nattokinase not only prevents hypertension and decreases the risk of heart disease, but it can also reduce existing symptoms of hypertension and work as an adjunctive treatment. The International Journal of Molecular Sciences has demonstrated that nattokinase prevents chronic heart disease. To get a general idea of what to expect, this study determined that the fibrinolytic activity of nattokinase took between 2 and 8 hours to come true. The consumption of nattokinase through natto itself can have a similar effect on blood circulation and fibrinogen levels, although dietary supplements provide a therapeutic-level dose and food doses can be more difficult to quantify.
Nattokinase has even shown promise as a substance useful for dissolving amyloid fibrils, protein compounds related to diseases such as Alzheimer's and dementia. Nattokinase is generally safe, but the enzyme's powerful effects can cause complications in people with certain health conditions. Although nattokinase doesn't increase blood pressure, it may not be suitable for people with high blood pressure, if those people have high blood pressure or are going to have surgery soon. When soy undergoes fermentation, the bacteria used activates nattokinase, giving the food its cheese-like flavor and a range of scientifically backed health benefits.
There is not enough research to indicate that nattokinase is safe for pregnant or breastfeeding women. Nattokinase is an anticoagulant substance, so its consumption in large quantities is not recommended if you have a bleeding disorder or are about to undergo surgery. Similarly, nattokinase can be used as a protective agent against thrombosis, or a condition in which blood clots clog arteries (usually in the extremities) and cause an ischemic stroke. If you have low blood pressure or are taking medicines to lower it, be sure to talk to your doctor before taking nattokinase.
The research also provides new evidence supporting nattokinase as a supplement to prevent and treat high blood pressure. When nattokinase improves hypertension, it effectively improves the chance of maintaining healthy kidneys. In the United States, nattokinase is generally administered in the form of a small tablet administered in an oral dose.