It's often argued that the best time to take Nattokinase is after dinner or before bed. You may not like to eat foods with natto before bed, but it's easy to do so with supplements. Natto foods have a very distinctive smell and taste, so you have to consider where and when to eat them. If you have a serious allergic reaction or if any of your symptoms seem life-threatening, call 911 and seek immediate medical help. The underlying pathological change shared by many cardiovascular diseases is atherosclerosis, which is the main cause of heart disease and stroke.32 Therefore, drugs that have anti-atherosclerotic effects would have broad clinical relevance; however, such drugs are difficult to obtain.
Nattokinase seems to be one of those drugs that have such promising anti-atherosclerotic and lipid-lowering effects...