Nattokinase is an enzyme that comes from a Japanese food called natto. Natto is made from cooked soybeans that have been fermented with a type of bacteria. Nattokinase can thin the blood and help dissolve blood clots. Nattokinase dissolves blood clots by directly hydrolyzing the fibrin substrate.
and plasmin. It converts endogenous prourokinase to urokinase (uPA). It also degrades the plasminogen activator inhibitor (PAI-) and increases the level of the tissue plasminogen activator (t-PA). Nattokinase can help prevent blood clots, lower blood pressure, and play a role in treating Alzheimer's disease.
Several studies support that nattokinase helps thin the blood and prevent the formation of blood clots. The enzyme does this by breaking down fibrin, which is a protein responsible for coagulation. To safely take natural medicines, including nattokinase, inform your healthcare providers and pharmacists of any changes in medications. While there are some small short-term studies on nattokinase, larger, well-designed studies are needed.
Nattokinase has the potential to simplify drug use and improve patient compliance with prevention and treatment. of CVDs. Nattokinase (NK), a powerful protein that dissolves blood clots and is used to treat cardiovascular diseases, is produced by the bacteria Bacillus subtilis during the fermentation of soybeans to produce Natto. Nattokinase, which is also sold as a dietary supplement to promote heart health, the side effects of nattokinase are generally mild, but may increase the risk of bleeding.
Intervention with serrapeptase and nattokinase to alleviate the physiopathology of Alzheimer's disease in a rat model. Before taking nattokinase, contact your pharmacist or healthcare provider to help you achieve your health goals safely. For this reason, there are no guidelines on the appropriate dosage for taking nattokinase for any condition. In addition to reducing stroke risk factors, such as high blood pressure and blood clots, nattokinase is associated with a decrease in von Willebrand factor (vWF) in people assigned as women at birth.
Although research is still ongoing, animal studies show that nattokinase can degrade amyloid fibrils, fibrous proteins that bind to each other and are involved in the progression of Alzheimer's and Parkinson's diseases. Several studies have demonstrated that nattokinase can be an all-natural, safe and affordable treatment for cardiovascular diseases. A small clinical trial of nattokinase in people without cardiovascular disease found no significant benefit in preventing heart disease. Now that you know what nattokinase is, let's look at some of the potential benefits of this supplement. If you have difficulty swallowing pills, nattokinase may also be available in other dosage forms, such as powder.
Nattokinase has also been shown to reduce acetylcholinesterase activity and inflammatory markers associated with neurodegenerative diseases. Nattokinase appears to be one of those drugs that have such promising anti-atherosclerotic and lipid-lowering effects.
