Nattokinase has the distinctive ability to make blood and other blood components less sticky. Thus, nattokinase has been shown in animal and human studies to reduce blood clotting and plaque build-up in arteries. Clinical study on the effect of nattokinase on atherosclerosis and hyperlipidemia of the carotid arteries All enrolled patients came from the outpatient service of the Department of Traditional Chinese Medicine of the third affiliated hospital of Sun Yat-sen University. Using the random selection method, all patients were randomly assigned to one of two groups: the nattokinase (NK) group and the statins (ST) .Patients in the NK group were given NK at a daily dose of 6000 FU and patients in the ST group were treated with statins (20 mg of simvastatin) per day.
The duration of treatment was 26 weeks. Before and after treatment, the average intimate thickness of the common carotid artery (CCA-IMT), the size of the carotid plate and the blood lipid profile of the patients were measured. This effect on atherosclerotic lesions is large enough to be suspicious, given that nattokinase is a commonly used supplement and the dose used is not excessively high. However, it seems that we are seeing a lot of this kind of thing these days; sometimes the importance goes unnoticed, but it is also sometimes a problem of the study that will be corrected later.
It's hard to know what it is without significant extra effort. Does treatment with bisphosphonates really extend life expectancy by five years? Did it really go unnoticed despite its widespread use in older people? Despite its widespread use, is fisetin really a senolytic compound that is significantly effective in humans? Has the very high senolytic dose compared to the usual supplement dose managed to hide this property? How have nearly twenty years of intense development and use of dasatinib, a chemotherapy drug, passed without anyone realizing that it destroyed enough senescent cells to improve health and measure aging in mice and people? And so on. I think it's likely that the macrophages in the plaque are there because they're just trying to do their job of fighting infections. Nattokinase and other interventions may have limited efficacy because the infection has not resolved.
So aren't all supplements snake oil? It's interesting to see how your opinions evolve. I eat natto regularly; I understand why some people prefer to obtain the active components of natto in the form of supplements (nattokinase, spermidine, K2, PQQ), since it's an acquired flavor (I enjoy it with spicy mustard and a little tamari). In addition, for therapeutic use (as opposed to for prevention) it is necessary to know the exact dose and, possibly, to obtain a much higher dose than that available with a normal serving. I take nattokinase, among other things. It has a low price and 6000 UF a day is what was used in the study originally published by Reason.
There's a lot of snake oil in the supplement industry, but some compounds have their merit. The key lies in the details and evaluation of journal publications. Linda, you should take serapeptase along with nattokinase, since both go well together. Restart your nattokinase dose, but take it together with a dose of 500,000 SPU a day (30 minutes before eating) and the enzyme serapeptase will help remove debris that seeps from plaques and will also remove accumulated fibrogen that contributes to blockages.
Try a good brand, such as Arthur Andrew Medical, that you can order on iherb, not a Chinese one. I did this last year along with a vegan diet and, although I lost quite a bit of weight, it cleared me up right away. I'd like to start with nattokinase, but I got cancer by eating soy protein isotopes. It's worth thinking about Linda's anecdote about going blind. Years ago I heard an anecdote about a stroke supposedly caused by serrapeptase.
Could enzymes themselves degrade something in the fibrous layers of plaques, causing them to break and, in fact, causing a clot? Or could they dislodge a pre-existing clot? In any case, it should be noted that the administration of nattokinase did not prevent Linda's occlusion or dissolve it in a timely manner to avoid problems. The only eye research I have done on nattokinse is that it can be used in animal studies to cause vitreous detachment. There is a report of a case of cerebral hemorrhage caused by the combination of 400 mg (I think) of nattokinase with aspirin. It's probably not a good idea to combine things.
Some research suggests that you need to take vitamin K2 if you are taking nattokinase. Natto continues to dissolve plaque and could damage arteries. I also take 400 mcg of vitamin K2, derived from natto, per day and 4000 UF of nattokinase a day, which I can increase to 6000 or 8000 if my planned CSC scan indicated the presence of calcified plaque. I also take 400 mcg of vitamin K2, derived from natto, a day and 4000 UF of nattokinase a day, an amount that I can increase to 6000 or 8000 if my planned CAC scan indicates the presence of calcified plaque.
Nattokinase dissolves blood clots through the process of fibrinolysis (dissolution of fibrin). Additional benefits include lowering blood pressure, reducing atherosclerosis and inhibiting platelet aggregation. Because of the multiple beneficial cardiovascular effects, nattokinase can be used in the prevention and treatment of cardiovascular diseases. Check with your doctor before taking nattokinase in supplement form if you are currently using these or other types of medications.
In addition, people with bleeding disorders, such as hemophilia, and people with low blood pressure should use nattokinase products with caution. Nattokinase has been shown to break down biofilms created by bacteria and yeasts, such as Candida albicans. I recently sent an email inquiry to the sole principal investigator at USC (Howard Neil Hodis) about an ongoing randomized controlled trial (mentioned above) on the effects of nattokinase on the progression of atherosclerosis and cognitive decline. It was also observed that nattokinase can limit the area of acute strokes and preserve surrounding brain tissue.
Atherosclerosis, or the narrowing of the arteries due to plaque buildup, is a common feature of cardiovascular disease. There is also some evidence to suggest that nattokinase may protect the brain health of people who have suffered an ischemic stroke. This shows that nattokinase may be a more effective treatment in the treatment of atherosclerosis than the drugs currently available on the market. Nattokinase (NK), known as a potent fibrinolytic and antithrombotic agent, has been shown to have anti-atherosclerotic and lipid-lowering effects.
Nattokinase also shows great potential for improving the respiratory health of people with chronic sinusitis, bronchitis, asthma, and chronic obstructive pulmonary disease. In addition, nattokinase has been shown to reduce atherosclerosis to a greater extent than statin therapy (powerful lipid-lowering drugs).). Nattokinase (NK), the most active ingredient in natto, has a variety of favorable cardiovascular effects and its consumption has been linked to a reduction in mortality from cardiovascular diseases.
